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Related Concept Videos

Introduction to Language of Pathophysiology ll01:17

Introduction to Language of Pathophysiology ll

This lesson explores key terms that describe how diseases progress, their outcomes, and their distribution in populations.Diagnostic tests identify diseases and monitor treatment. These include blood and urine tests, biopsies, imaging (X-ray, MRI), and detection of infectious agents.Remission is a reduction or disappearance of symptoms.Exacerbation refers to the worsening of symptoms, such as increased wheezing during an asthma attack.A precipitating factor triggers an acute episode, while a...
Introduction to Language of Pathophysiology l01:25

Introduction to Language of Pathophysiology l

Pathophysiology investigates how biological mechanisms—typically starting at the cellular level—disrupt normal bodily functions. It bridges anatomy and physiology to explain the progression of disease. With this foundation, it is important to understand the following key terms used to describe disease processes: Diagnosis:The process of identifying a disease using clinical evaluation, including signs (objective evidence like rashes), symptoms (subjective experiences like pain), laboratory test...
Colonisation of Pathogens01:25

Colonisation of Pathogens

Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
Cirrhosis II: Pathophysiology01:24

Cirrhosis II: Pathophysiology

Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to structural...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...

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Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
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Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Published on: July 11, 2025

[Pathology- a new revival].

Iris Barshack1

  • 1Department of Pathology, Sheba Medical Center, Israel. barshack@sheba.health.gov.il

Harefuah
|July 27, 2013
PubMed
Summary
This summary is machine-generated.

Pathology is evolving with molecular pathology advancements, crucial for personalized cancer therapy and diagnostics. New tissue banking initiatives support both clinical service and research in this dynamic medical field.

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Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
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Published on: December 18, 2016

Area of Science:

  • Pathology
  • Molecular Pathology
  • Medical Diagnostics

Context:

  • Pathology remains a cornerstone of medicine, evolving beyond traditional roles.
  • Increasing medical specialization highlights pathology's enduring breadth.
  • The rise of molecular pathology is transforming disease characterization and diagnosis.

Purpose:

  • To highlight the significant changes and expanding scope within the field of pathology.
  • To emphasize the critical role of molecular pathology in modern medicine, particularly in personalized cancer therapy.
  • To discuss the growing importance of tissue collection and banking for diagnostic and research applications.

Summary:

  • Pathology, the study of disease, is undergoing significant transformation driven by molecular pathology.
  • Molecular pathology enables personalized cancer therapies by predicting patient response to treatments.
  • Tissue banking initiatives are expanding to support both clinical diagnostics and research endeavors.

Impact:

  • Enhanced diagnostic capabilities and personalized treatment strategies in oncology.
  • Advancement of medical research through comprehensive tissue repositories.
  • Strengthened foundation for future medical discoveries and improved patient outcomes.