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Published on: February 6, 2011
Malakoplakia mimics urinary bladder cancer: a case report.
Ana Ristić-Petrović1, Slavica Stojnev, Ljubinka Janković-Velicković
1Institute of Pathology, Faculty of Medicine, University of Nii, Nih, Serbia.
Vojnosanitetski Pregled
|July 27, 2013
Summary
Malakoplakia is a rare inflammatory bladder condition that can mimic cancer. Early diagnosis via biopsy and prompt antibiotic treatment are crucial for effective management.
Area of Science:
- Urology
- Pathology
- Inflammatory Diseases
Background:
- Malakoplakia is a rare chronic inflammatory condition.
- It can present as a bladder tumor, leading to misdiagnosis.
- Differential diagnosis is critical due to its potential to mimic malignancy.
Observation:
- A middle-aged woman presented with persistent macrohematuria.
- Cystoscopy revealed a polypoid bladder mass.
- Biopsy showed characteristic histiocytes with Michaelis-Gutmann inclusions.
Findings:
- Microscopic examination confirmed malakoplakia.
- Immunohistochemistry identified CD68-positive macrophages.
- The findings were consistent with bladder malakoplakia.
Implications:
- Bladder malakoplakia should be considered in patients with persistent UTIs and suspicious cystoscopic findings.
- Early diagnosis and antibiotic therapy can prevent misdiagnosis and surgical intervention.
- Prompt treatment can avert potential complications associated with malakoplakia.
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