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Updated: May 9, 2026

Asymmetrical Flow Field-Flow Fractionation for Sizing of Gold Nanoparticles in Suspension
Published on: September 11, 2020
Determination of the functioning parameters in asymmetrical flow field-flow fractionation with an exponential channel
1Institut Européen des Membranes, UMR 5635 (CNRS, UM2, ENSCM), Université Montpellier 2, 2 Place Eugène Bataillon, F-34095 Montpellier Cedex 5, France. philippe.dejardin@univ-montp2.fr
Abstract:
The flow conditions in normal mode asymmetric flow field-flow fractionation are determined to approach the high retention limit with the requirement d≪l≪w, where d is the particle diameter, l the characteristic length of the sample exponential distribution and w the channel height. The optimal entrance velocity is determined from the solute characteristics, the channel geometry (exponential to rectangular) and the membrane properties, according to a model providing the velocity fields all over the cell length. In addition, a method is proposed for in situ determination of the channel height.
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