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Paroxysmal kinesigenic dystonic choreoathetosis associated with a thalamic infarct
1Neurological Institute, Columbia Presbyterian Medical Center, New York, New York.
Abstract:
We describe a patient with the development of paroxysmal kinesigenic dystonic choreoathetosis (PKDC) after a thalamic infarct. PKDC consists of brief episodes of dystonia or choreoathetosis triggered by movement. PKDC improves with anticonvulsants, and in some cases, with L-Dopa or anticholinergics. We review PKDC, and relate its salient features to idiopathic and secondary torsion dystonia. We postulate a similar underlying pathophysiology.