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3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse
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3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse

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Imaging findings of intraventricular and ependymal lesions

L Vandesteen1, A Drier, D Galanaud

  • 1Department of Neuroradiology, Pitié-Salpêtrière Hospital, AP-HP, 47-83, boulevard de l'Hôpital, 75013 Paris, France.

Journal of Neuroradiology = Journal De Neuroradiologie
|July 27, 2013
PubMed

Insights

This review details intraventricular and ependymal lesions, including tumors, cysts, infections, and inflammatory conditions. It emphasizes key neuroimaging findings for accurate diagnosis and differential diagnosis of these rare brain disorders.

Area of Science:

  • Neurology
  • Radiology
  • Pathology

Background:

  • Intraventricular and ependymal lesions encompass diverse pathologies: tumoral, cystic, vascular, infectious, and inflammatory.
  • Diagnosis relies on location, patient age, and computed tomography (CT) and magnetic resonance imaging (MRI) patterns for tumoral and cystic diseases.
  • MRI findings for infectious diseases are corroborated by clinical history, immune status, and laboratory results.

Purpose of the Study:

  • To provide a comprehensive description of intraventricular and ependymal disorders.
  • To highlight key neuroimaging findings for differential diagnosis.
  • To present a diagnostic approach for intraventricular focal masses and ependymal dissemination.

Main Methods:

  • Review of existing literature on intraventricular and ependymal lesions.
  • Analysis of neuroimaging characteristics (CT and MRI).
  • Development of a diagnostic strategy based on lesion characteristics and location.

Main Results:

  • Tumoral and cystic lesions are diagnosed using location, age, and imaging patterns.
  • Infectious lesions require integration of clinical, immune, and laboratory data with MRI findings.
  • Associated intracranial lesions aid in diagnosing specific conditions like Sturge-Weber syndrome and systemic diseases.

Conclusions:

  • A structured diagnostic approach, considering lesion morphology (solid/cystic), origin, and location, aids in differentiating intraventricular masses.
  • Ependymal enhancement suggests ventriculitis, tumor spread, or infectious/inflammatory conditions.
  • Accurate interpretation of neuroimaging is crucial for diagnosing the wide spectrum of intraventricular and ependymal lesions.
Keywords:
DiagnosisDiseaseEpendymaIntraventricularMRI

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