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Updated: May 9, 2026

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches
Published on: October 8, 2021
Robust molecular micro-capsules for encapsulating and releasing hydrophilic contents
Francisco Vera1, Marta Mas-Torrent, Civan Avci
1Institut de Ciència de Materials de Barcelona (ICMAB-CSIC) and Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Campus de la UAB, 08193 Bellaterra, Spain.
Abstract:
The hydrophobic-amphiphilic self-assembly approach has been employed to prepare molecular micro-capsules simply by cooling down an emulsion, in a hot polar solvent medium, of a melted compound having two very well-distinguished units, both with highly non-polar and hydrophobic characteristics. The resulting micro-capsules are very stable and robust both in suspension and under dry conditions. Further, such micro-capsules can effectively encapsulate hydrophilic compounds which can later on be easily released upon the application of UV-light.
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