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Changes of lens protein particles during development and reversal of galactose cataracts. Study by laser scattering
M Kaneda1, Y Majima, H Hattori
1Department of Ophthalmology, School of Medicine, Fujita-Gakuen Health University, Aichi, Japan.
Ophthalmic Research
|January 1, 1990
Abstract:
3-week-old Wistar rats weighing about 50 g were fed a 38% galactose diet which was subsequently replaced with a normal diet. We measured the protein particle diameters and the scattered light intensity in the transparent part of galactose cataractous lenses. The scattered light intensity of small particles with a diameter of approximately 0.02 microns, corresponding to alpha-crystallin, decreased with a galactose diet, whereas it increased with a normal diet.