Effects of indoor air pollution on lung function of primary school children in Kuala Lumpur
1Department of Paediatrics, Faculty of Medicine, National University of Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur.
Insights
Childhood lung function in Kuala Lumpur is influenced by height, weight, age, and sex. Asthma and exposure to secondhand smoke significantly impair lung capacity, particularly FEF25-75.
Area of Science:
- Pediatric Pulmonology
- Environmental Health
- Epidemiology
Background:
- Assessing lung function in children is crucial for understanding respiratory health.
- Environmental and host factors can significantly impact pediatric lung development and performance.
Purpose of the Study:
- To evaluate lung function parameters in primary school children in Kuala Lumpur.
- To identify predictors of lung function, including anthropometric, ethnic, and environmental factors.
- To investigate the association between asthma, secondhand smoke exposure, and lung function.
Main Methods:
- Cross-sectional study involving 1,214 children (spirometry) and 1,414 children (peak expiratory flow).
- Measurements included forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEF25-75, and PEFR.
- Multiple regression models analyzed predictors and associations with host and environmental factors.
Main Results:
- Standing height, weight, age, and sex were primary predictors of lung function.
- Asthma was linked to reduced FEV1, FEF25-75, and PEFR.
- Exposure to secondhand smoke (shared rooms with smokers) correlated with lower FEF25-75.
- Wood/kerosene stove exposure showed association with decreased lung function, unlike mosquito repellents.
Conclusions:
- Childhood lung function is influenced by a combination of physical characteristics and environmental exposures.
- Asthma and passive smoking are significant detrimental factors for lung health in children.
- Further research into specific environmental exposures like indoor air pollutants is warranted.
Abstract:
In a cross-sectional study of 7-12 year-old primary school children in Kuala Lumpur city, lung function was assessed by spirometric and peak expiratory flow measurements. Spirometric and peak expiratory flow measurements were successfully performed in 1,214 and 1,414 children, respectively. As expected, the main predictors of forced vital capacity (FVC), forced expiratory volume in one second (FEV1), forced expiratory flow between 25% and 75% of vital capacity (FEF25-75), and peak expiratory flow rate (PEFR) were standing height, weight, age, and sex. In addition, lung function values of Chinese and Malays were generally higher than those of Indians. In multiple regression models which included host and environmental factors, asthma was associated with significant decreases in FEV1, FEF25-75, and PEFR. However, family history of chest illness, history of allergies, low paternal education, and hospitalization during the neonatal period were not independent predictors of lung function. Children sharing rooms with adult smokers had significantly lower levels of FEF25-75. Exposures to wood or kerosene stoves were, but to mosquito repellents were not, associated with decreased lung function.
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