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Characterization of Vascular Morphology of Neovascular Age-Related Macular Degeneration by Indocyanine Green Angiography
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Choroidal neovascularization in 36 eyes of children and adolescents

P Rishi1, A Gupta, E Rishi

  • 1Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Eye (London, England)
|July 27, 2013
PubMed

Insights

Choroidal neovascularization (CNV) in children and adolescents often leads to vision loss. Post-inflammatory causes and subfoveal locations are common, but treatment shows a high regression rate.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Retinal Diseases

Background:

  • Choroidal neovascularization (CNV) is a significant cause of visual impairment in pediatric populations.
  • Understanding the clinical characteristics and outcomes of CNV in children is crucial for effective management.

Purpose of the Study:

  • To delineate the clinical features and visual outcomes of choroidal neovascularization (CNV) in pediatric and adolescent patients.
  • To identify key demographic, etiological, and anatomical factors associated with CNV in this age group.

Main Methods:

  • Retrospective review of 36 eyes from 27 patients under 18 years old diagnosed with CNV.
  • Confirmation of CNV via clinical diagnosis and fundus fluorescein angiography (FFA).
  • Evaluation of anatomical outcomes (regression, persistence, recurrence) and best-corrected visual acuity (BCVA).

Main Results:

  • Male predominance (63%) and bilateral involvement (33.3%) were observed.
  • The most frequent cause was post-inflammatory CNV (41.7%), often subfoveal (80.5%).
  • A high regression rate was noted with treatment, with recurrence in 8.3% of eyes.

Conclusions:

  • CNV in children and adolescents is associated with significant visual decline.
  • Key features include male predominance, post-inflammatory etiology, bilateral presentation, and subfoveal location.
  • Treatment demonstrates a high regression rate, with limited need for re-treatment.
Abstract

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