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Water soluble fluorescence quantum dot probe labeling liver cancer cells

Baoxing Chang1, Xianjun Yang, Fang Wang

  • 1Basic Medical College, Tianjin Medical University, Tianjin, 300070, China.

Journal of Materials Science. Materials in Medicine
|July 27, 2013
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...