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Updated: May 9, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
[Sun addiction, its death blow and the multitude of sunscreens]
C Piérard-Franchimont1, T Hermanns-Lê, G E Plérard
1CHR hutois, Service de Dermatologie, Huy, France. claudine.franchimont@ulg.ac.be
Abstract:
Any mismatch between the innate cutaneous pigmentation and lifetime behaviour regarding sun exposure is a serious challenge for the skin. Sunbaths and sun parlours combine their deleterious effects. The risks for inflammatory reactions (sunburns and other photoreactions), chronic photoageing, skin field photocancerogenesis, some equivocal tumours (actinic keratosis, actinic porokeratosis,...) and overt skin cancers (basal cell carcinoma, squamous cell carcinoma, melanoma) are common conditions. For the public at large and medias, sunscreens aim at preventing these issues. Clearly, each of these goals is not fully achieved.
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