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Updated: May 9, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
[Neuropsychological tests in a group of patients with ischaemic heart disease]
Agnieszka Stetkiewicz-Lewandowicz1, Alina Borkowska
1Zakład Psychologii Lekarskiej Uniwersytetu Medycznego w Lodzi Kierownik.
Insights
Patients with ischemic heart disease (IHD) experience significant cognitive impairments, including issues with working memory and verbal recall. These deficits can impact daily functioning and adherence to medical advice, highlighting the need for cognitive assessments in IHD patients.
Area of Science:
- Cardiology
- Neuropsychology
- Neurology
Background:
- Ischemic heart disease (IHD) is a leading global cause of mortality and morbidity.
- IHD is associated with an increased risk of central nervous system disturbances.
- Impaired neuropsychological test results can predict cardiac relapse.
Purpose of the Study:
- To assess cognitive functions, including working memory, executive functions, and verbal memory, in patients with IHD compared to healthy controls.
- To investigate the relationship between prefrontal cortex activity and cognitive deficits in IHD.
Main Methods:
- The Wisconsin Card Sorting Test (WCST) was used to evaluate executive functions and cognitive flexibility.
- The Rey Auditory Verbal Learning Test (RAVLT) was employed to assess immediate and delayed verbal memory.
- Cognitive functions were evaluated in patients with IHD and a control group of healthy subjects.
Main Results:
- Patients with IHD exhibited significant cognitive dysfunctions compared to the control group.
- Working memory and executive functions were notably impaired in the IHD cohort.
- Both immediate and delayed verbal memory showed significant deficits in patients with IHD.
Conclusions:
- Cognitive dysfunctions are prevalent among individuals with IHD.
- Impairments in working memory and executive functions pose risks for understanding, learning, and adhering to medical recommendations, potentially leading to rehospitalization.
- Routine cognitive evaluation and neurocognitive rehabilitation are recommended for IHD patients.
Aim:
Ischaemic heart disease (IHD) tops the list of sick and death rates all over the world. IHD brings the risk of central nervous system disturbances. On the other hand lower neuropsychological tests results enable to predict cardiac relapse. We assess the neuropsychological function such as working memory and executive functions, associated with prefrontal cortex activity, as well as direct and delayed verbal memory in patients with ischemic heart disease vs. healthy subjects.
Methods:
The following neuropsychological tests were applied in the study for evaluation of cognitive functions: the Wisconsin Card Sorting Test (WCST) and the Rey Auditory Verbal Learning Test (RAVLT).
Results:
In the patients with IHD a significant intensification of cognitive dysfunctions (working memory and executive dysfunctions also immediate and delayed memory) was observed in comparison with the control group of healthy subjects.
Conclusions:
Cognitive dysfunctions are widespread effect among IHD patients. Working memory and executive functions disturbances are especially dangerous in this group because they can result in problems with understanding, learning new information and difficulties in following medical recommendations which may cause consecutive hospitalisations. The seriousness of cognitive disturbances consequences motivate to evaluate all patients and initiate neurocognitive rehabilitation programs when needed.
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