Related Experiment Video
Updated: May 9, 2026

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats
Published on: August 15, 2025
Aortic aneurysm rupture as a rare complication of granulomatosis with polyangiitis: a case report
Nobuo Ohta1, Takayoshi Waki, Shigeru Fukase
1Department of Otolaryngology, Yamagata University Faculty of Medicine, 2-2-2 Iida-nishi, Yamagata, 990-23, Japan. noohta@med.id.yamagata-u.ac.jp.
Introduction:
Granulomatosis with polyangiitis is characterized by systemic inflammation of medium and small blood vessels. Aortic involvement in granulomatosis with polyangiitis is extremely rare. As far as we know this is the first reported case of successful treatment in a patient with granulomatosis with polyangiitis complicated with aortic aneurysm rupture.
Case Presentation:
We describe a case of granulomatosis with polyangiitis in a 38-year-old Japanese man who developed an aortic aneurysm rupture 22 years after disease onset. The patient was operated on and a J-graft was inserted. He recovered uneventfully.
Conclusion:
Recommendations in regard to, and consideration of, aortic involvement should be kept in mind in the long-term careful follow up of granulomatosis with polyangiitis.
Related Concept Videos
Aneurysm III: Interprofessional Care
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm I: Introduction
Aortic Regurgitation I: Introduction
Aortic Regurgitation III: Medical Management
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
