Related Experiment Video
Updated: May 9, 2026
In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
Published on: January 20, 2019
Plasma cells for hire: prior experience required
1Integrated Department of Immunology, K516B, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA. hagmanj@njhealth.org
Activation of IgG⁺ memory B cells accounts for much of the antibodies in secondary immune responses. Here, Kometani et al. (2013) demonstrate that reduced amounts of Bach2 in antigen-experienced memory B cells control the robust production of IgG1⁺ plasma cells.
Activation of IgG⁺ memory B cells accounts for much of the antibodies in secondary immune responses. Here, Kometani et al. (2013) demonstrate that reduced amounts of Bach2 in antigen-experienced memory B cells control the robust production of IgG1⁺ plasma cells.
