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Updated: May 9, 2026
08:47
Spectral Confocal Imaging of Fluorescently tagged Nicotinic Receptors in Knock-in Mice with Chronic Nicotine Administration
Published on: February 10, 2012
The relationship between nicotine cessation and mental disorders in a nationally representative sample
Sean Donald1, Hayley Chartrand, James M Bolton
1Department of Psychiatry, University of Manitoba, Winnipeg, Manitoba, Canada.
Journal of Psychiatric Research
|July 30, 2013
Summary
Quitting nicotine dependence reduces the likelihood of mood and substance use disorders. Nicotine cessation also improves physical and mental quality of life compared to current dependence.
Area of Science:
- Psychiatry and Public Health
- Epidemiology
- Addiction Medicine
Background:
- Nicotine dependence is a significant public health concern.
- Understanding the relationship between nicotine cessation, mental health, and quality of life is crucial for effective interventions.
Purpose of the Study:
- To investigate the association between nicotine dependence cessation and the prevalence of Axis I and II mental disorders.
- To examine the impact of nicotine cessation on quality of life.
- To compare individuals who have ceased nicotine use with those currently dependent and lifetime abstainers.
Main Methods:
- Utilized data from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), Wave 2 (N = 34,653).
- Employed multivariate logistic regression to analyze the relationship between nicotine cessation, mental disorders, and quality of life.
- Compared nicotine cessation group (past-year abstinent) against current nicotine dependence and lifetime abstainers.
Main Results:
- Nicotine cessation was linked to a lower likelihood of past-year mood disorders (AOR=0.64) and substance use disorders (AOR=0.65) compared to current dependence.
- Individuals who ceased nicotine use were less likely to have narcissistic and borderline personality disorders.
- Nicotine cessation was associated with significant improvements in both physical (beta=1.65) and mental (beta=2.17) quality of life.
Conclusions:
- Nicotine dependence cessation is associated with a reduced prevalence of several mental disorders.
- Cessation of nicotine use leads to an improved quality of life.
- Findings support public health policies promoting smoking and nicotine cessation programs.
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