Related Experiment Video
Updated: May 9, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Acute aortic dissection type A with acute coronary involvement: a novel classification
Ying-Fu Chen1, Tsu-Ming Chien, Cai-Pei Yu
1Division of Cardiovascular Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung Taiwan.
Insights
Acute coronary involvement in aortic dissection type A is a serious condition. Patients with this complication are younger and have higher rates of aortic regurgitation, aiding surgical decisions.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Disease
Background:
- Acute aortic dissection (AAD) type A can involve the coronary arteries, posing a significant risk.
- Acute coronary involvement (ACI) in AAD type A is a potentially fatal complication.
- Understanding the characteristics of ACI in AAD type A is crucial for patient management.
Purpose of the Study:
- To determine the specific characteristics of patients experiencing acute coronary involvement (ACI) secondary to acute aortic dissection (AAD) type A.
- To identify demographic, clinical, and pathological features associated with ACI in AAD type A.
Main Methods:
- Retrospective analysis of 142 patients surgically treated for AAD type A between 1997 and 2011.
- Inclusion of 20 patients (14.1%) who presented with ACI.
- Comparison of patient demographics, clinical presentation, and outcomes between groups with and without ACI.
Main Results:
- Patients with ACI were significantly younger (51.8 vs. 61.0 years) and had a higher rate of aortic regurgitation (95.0% vs. 53.5%).
- Intramural hematoma was less common in patients with ACI (5.0% vs. 32.8%).
- In-hospital mortality rates were similar between patients with and without ACI (20.0% vs. 19.7%).
Conclusions:
- Acute coronary involvement in AAD type A is not invariably linked to coronary malperfusion.
- Key differentiating factors for ACI include younger age, higher aortic regurgitation, and lower prevalence of intramural hematoma.
- A novel 4-category classification scheme based on surgical pathology is proposed to aid treatment decisions for this patient cohort.
Background:
Acute coronary involvement (ACI) due to acute aortic dissection (AAD) type A is potentially fatal. We examined selected patients with AAD type A, which had evolved over 14 years, and acute coronary involvement. The purpose of this study was to determine the characteristics of patients with ACI due to AAD type A.
Methods:
Between 1997 and 2011, we recruited 20 patients (14.1%) with ACI (14 men, 6 women; mean age: 51.8 ± 11.8 years; age range: 35-79 years) from 142 patients who had undergone surgical repair of AAD type A.
Results:
We propose a novel 4-category classification scheme based on the surgical pathological findings. The right coronary artery was involved in 15 patients, and the left was involved in 5 patients. Fourteen patients had preoperative myocardial ischemia. In the other 6 patients, acute coronary involvement was found intraoperatively. Patients with ACI were significantly younger than those without ACI (51.8 ± 11.8 vs. 61.0 ± 11.8; p = 0.001), a lower prevalence of intramural hematoma (5.0% vs. 32.8%; p = 0.011), a higher aortic regurgitation rate (95.0% vs. 53.5%; p = 0.001). Patients presenting with ACI had an in-hospital mortality rate of 20.0% (4/20), while those without ACI had an in-hospital mortality rate of 19.7% (24/122).
Conclusions:
Acute coronary involvement due to AAD type A is not always associated with coronary malperfusion. Patients with ACI were much younger, had a higher aortic regurgitation rate, and, less commonly, had intramural hematoma. This new classification scheme would make it more convenient for surgeons to decide on treatment options for this special cohort.
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