[Büschke-Loewenstein tumor during pregnancy. Apropos of 2 cases]

The authors report two cases of Büschke-Loewenstein tumors during pregnancy. The considerable development of this giant condyloma requires a caesarean section, to prevent a possible neonatal contamination of the newborn. The course is complicated with recurrences and the treatments are disappointing during the pregnancy. After birth, regression may be spontaneous (case no. 2). Most of the time, after a surgical biopsy is performed, for an accurate pathological examination, electrocoagulation, cryotherapy or CO2 laser result in the cure of the patient. Monitoring must be long-lasting because of the risk of spinocellular degeneration and node metastases. The papillomavirus in cause is the type HPV 6 or 16 and a few cases are described with types 16, 18, 32. The high frequency of accumulated condylomas and the possibility of rapid spread make this disease very current: the human immunodeficiency virus is one of the cofactors of transformations into verrucous carcinoma.