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Long-term satisfaction and medication dependence after antireflux surgery
Yinin Hu1, Brian Ezekian1, Kristen M Wells2
1Department of Surgery, University of Virginia School of Medicine, Charlottesville, Virginia.
The Annals of Thoracic Surgery
|July 30, 2013
Summary
Antireflux surgery offers significant short-term relief for GERD patients, with high satisfaction and medication-free rates at 5 years. However, these benefits diminish by the 10-year mark, indicating a need for long-term monitoring.
Area of Science:
- Gastroenterology
- Surgical Outcomes
- Patient-Reported Outcomes
Background:
- Gastroesophageal reflux disease (GERD) refractory to medical management often requires surgical intervention.
- Long-term outcomes of antireflux surgery are not well-documented.
- This study aimed to assess long-term patient satisfaction and medication dependence post-antireflux surgery.
Purpose of the Study:
- To evaluate long-term patient satisfaction after antireflux surgery.
- To determine the rate of medication dependence at 5 and 10 years post-surgery.
- To identify predictors of sustained positive outcomes.
Main Methods:
- Retrospective review of patients undergoing antireflux surgery for GERD (2000-2010).
- Long-term outcomes assessed via telephone surveys.
- Cox proportional hazards models used to analyze predictors of satisfaction and medication use at 5 and 10 years.
Main Results:
- At 5 years post-surgery, 82% of patients were satisfied and 83% were medication-free.
- By 10 years, satisfaction dropped to 59% and medication-free rates to 38%.
- No significant association found between patient demographics/surgical factors and long-term outcomes.
Conclusions:
- Antireflux surgery provides substantial short-term symptom improvement and high patient satisfaction.
- Long-term follow-up reveals a decline in both patient satisfaction and medication-free status.
- Sustained benefits of antireflux surgery decrease significantly beyond 5 years.
Keywords:
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