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Related Concept Videos

Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
Non-LTR Retrotransposons03:18

Non-LTR Retrotransposons

As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...

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Related Experiment Video

Updated: May 9, 2026

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
07:20

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Published on: December 21, 2012

Trace elements and endometriosis: the ENDO study.

Anna Z Pollack1, Germaine M Buck Louis, Zhen Chen

  • 1Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Health, 6100 Executive Blvd. Rockville, Maryland 20852, United States.

Reproductive Toxicology (Elmsford, N.Y.)
|July 30, 2013
PubMed
Summary
This summary is machine-generated.

Trace element levels show varied associations with endometriosis. Blood cadmium may reduce endometriosis risk, while urinary chromium and copper may increase it, warranting further investigation into these trace elements and endometriosis.

Keywords:
95% confidence intervalArsenicBMICICadmiumCdChromiumENDOEndometriosisHgIQCLODLeadMRIMercuryMetalsNHANESNISTNational Health and Nutrition Examination SurveyNational Institute of Standards and TechnologyORPbTrace elementsaORadjusted odds ratiobody mass indexcadmiumendometriosis: Natural History, Diagnosis and Outcomes Studyinternal quality controlleadlimits of detectionmagnetic resonance imagingmercuryodds ratio

Related Experiment Videos

Last Updated: May 9, 2026

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
07:20

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Published on: December 21, 2012

Area of Science:

  • Gynecology
  • Environmental Health
  • Biochemistry

Background:

  • Endometriosis is a common gynecological condition with multifactorial causes.
  • Research on the role of trace elements in endometriosis pathogenesis is limited.
  • Understanding environmental factors, such as trace elements, may offer new insights into endometriosis.

Purpose of the Study:

  • To investigate the association between specific trace elements and the diagnosis of endometriosis.
  • To compare findings between an operative cohort with surgically confirmed disease and a population cohort with MRI-diagnosed disease.

Main Methods:

  • A matched cohort study involving 473 women in the operative cohort and 131 women in the population cohort (aged 18-44 years).
  • Quantification of 20 urinary and 3 blood trace elements using inductively coupled plasma mass spectrometry.
  • Logistic regression analysis to estimate the adjusted odds ratios (aOR) of endometriosis for each element.

Main Results:

  • No significant associations were found between any trace element and endometriosis in the population cohort.
  • In the operative cohort, blood cadmium was associated with reduced odds of endometriosis (aOR=0.55).
  • Urinary chromium (aOR=1.97) and copper (aOR=2.66) were associated with increased odds of endometriosis in the operative cohort.

Conclusions:

  • Trace element associations with endometriosis differ between population-based and surgically confirmed cohorts.
  • Blood cadmium, urinary chromium, and urinary copper show potential links to endometriosis, highlighting the need for further research.
  • These findings suggest a complex role for trace elements in endometriosis and emphasize the importance of continued investigation.