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Related Experiment Videos

[14 years' experience with large-surface-area dialyzers].

G Giorcelli1, A Tricerri, G Vacha

  • 1Ospedale Maurizianø Umberto I, Torino, Divisione di Nefrologia e Dialisi.

Minerva Urologica E Nefrologica = the Italian Journal of Urology and Nephrology
|January 1, 1990
PubMed
Summary

High efficiency hemodialysis using large surface area dialyzers has shown excellent long-term patient survival rates. This individualized short dialysis schedule is safe and effective for uremic patients.

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[Clinical and metabolic features of renal calculi in adults in regard to age of onset].

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·1999

Area of Science:

  • Nephrology
  • Renal Replacement Therapy
  • Dialysis Technology

Context:

  • Hemodialysis treatments utilizing large surface area dialyzers were implemented in a dialysis unit starting in 1974.
  • A cohort of 129 uremic patients received treatment between September 1974 and August 1988.

Purpose:

  • To evaluate the long-term safety and efficacy of high-efficiency hemodialysis with large surface area dialyzers.
  • To assess patient survival rates and identify key technical parameters for implementing such a program.

Summary:

  • The study involved 129 uremic patients aged 16-72 years undergoing hemodialysis with large surface area dialyzers (>1.8 m2) and high blood flow rates (>300 ml/min), using bicarbonate buffer.
  • Patient survival rates were 95.3% at 1 year, 78.3% at 5 years, and 65.8% at 10 years.

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  • Key technical elements included high blood flow rates, large dialyzer surface area, and bicarbonate buffer. Automatic ultrafiltration control was noted as a preferred method.

    • Impact:

    • Demonstrates the long-term viability and safety of individualized short dialysis schedules in a large patient population.
    • Provides evidence for the effectiveness of high-efficiency hemodialysis in improving patient survival.
    • Highlights crucial technical considerations for successful implementation of advanced hemodialysis protocols.