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[Role of androgen in the elderly. Cardiovascular disease and androgen]

Hiroaki Kawano1

  • 1Faculty of Life Sciences, Kumamoto University, Japan.

Clinical Calcium
|July 30, 2013
PubMed

Insights

High cholesterol (hypercholesterolemia) is more common in women, yet cardiovascular disease is more prevalent in men. Sex hormones and genes likely influence these cardiovascular risk factors differently between sexes.

Area of Science:

  • Cardiovascular science
  • Endocrinology
  • Genetics

Context:

  • Hypercholesterolemia is a significant cardiovascular disease risk factor, affecting women more than men.
  • Cardiovascular disease (CVD) prevalence is higher in men despite lower hypercholesterolemia rates.
  • Hypertension and glucose intolerance may be more frequent in men, contributing to CVD sex differences.

Purpose:

  • To investigate the influence of sex hormones and sex-related genes on cardiovascular disease risk factors.
  • To elucidate the mechanisms behind sex-based disparities in cardiovascular disease development.

Summary:

  • This study examines the differential prevalence of cardiovascular disease risk factors between sexes.
  • It explores the potential roles of sex hormones and sex-linked genes in modulating these risk factors.
  • Understanding these factors is crucial for addressing atherosclerosis development.

Impact:

  • Findings will aid in developing targeted strategies to reduce atherosclerosis.
  • Provides insights into sex-specific cardiovascular disease prevention and treatment.
  • Highlights the importance of considering hormonal and genetic factors in cardiovascular health.

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