Lyonization in ophthalmology
Related Experiment Video
Updated: May 9, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
Wadakarn Wuthisiri1, Michelle D Lingao, Jenina E Capasso
1Wills Eye Institute, Philadelphia, Pennsylvania 19107, USA.
Purpose Of Review:
To describe the entity of Lyonization in ocular eye diseases, along with its clinical and counseling implications.
Recent Findings:
Several X-linked ocular diseases such as choroideremia, X-linked retinitis pigmentosa, and X-linked ocular albinism may have signs of Lyonization on ocular examination and diagnostic testing. These findings may aid in the proper diagnosis of ocular disease in both female carriers and their affected male relatives.
Summary:
Manifestations of Lyonization in the eye may help in the diagnosis of X-linked ocular diseases which may lead to accurate diagnosis, appropriate molecular genetic testing and genetic counseling.
Related Concept Videos
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Glaucoma: Overview
Accessory Structures of the Eye