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Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Compact Bone01:27

Compact Bone

Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Interval Level of Measurement00:55

Interval Level of Measurement

For effective statistical analysis, data are classified into four levels of measurement—nominal, ordinal, interval, and ratio.
Data measured using the interval scale are similar to ordinal level data because they have a definite arrangement. However, in the interval level of measurement, the differences between data values are meaningful even though the data does not have a starting point.
Temperature is measured using the interval scale. It is measurable data, and the difference between the...

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Intervals between bone density testing.

Ian R Reid1, Gregory D Gamble

  • 1Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
|July 30, 2013
PubMed
Summary
This summary is machine-generated.

For osteopenic women, fracture risk doubles approximately every 5 to 6 years. This finding helps determine optimal bone density testing intervals for managing osteoporosis risk.

Keywords:
BONE DENSITOMETRYFRACTURE RISKOSTEOPOROSIS

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Area of Science:

  • Endocrinology
  • Geriatrics
  • Radiology

Background:

  • Current clinical practices for bone density testing intervals in osteopenic women vary widely.
  • Decisions for osteoporosis treatment are increasingly based on absolute fracture risk.
  • Projecting future fracture risk is essential for determining appropriate bone density measurement (BMD) intervals.

Purpose of the Study:

  • To establish evidence-based intervals for serial BMD measurements in osteopenic women.
  • To utilize fracture risk modeling to guide clinical decision-making for osteoporosis management.

Main Methods:

  • Modeling fracture risk projections based on age and baseline bone mineral density (BMD).
  • Utilizing the Fracture Risk Assessment Tool (FRAX) to assess fracture risk.
  • Simulating scenarios for 65-year-old women with varying osteopenic BMD levels.

Main Results:

  • Bone loss in older women is estimated at approximately 1% annually.
  • A consistent doubling time of 5 to 6 years was observed for FRAX-assessed fracture risk.
  • This timeframe applies across a range of osteopenic baseline BMDs.

Conclusions:

  • A 5- to 6-year interval for BMD reassessment is suggested for stable osteopenic women.
  • Projecting fracture risk provides a logical basis for determining BMD testing frequency.
  • These findings offer practical guidance for managing osteoporosis and preventing fractures.