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Updated: May 9, 2026

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
[Correlation between TORCH infections and abnormal pregnant outcomes]
Qian-Qian Zhang1, Jun-Zhen Cheng, Feng-Hui Wang
1Medical College of Yan'an University, Yan'an 716000, China.
Objective:
To understand the correlation between TORCH infections and adverse pregnancy outcomes, so as to provide recommendations for birth defect interventions.
Methods:
The serum samples from 900 pregnant women were tested for TORCH-IgM by capture ELISA. The women with positive results were followed up and the outcomes of their pregnancies were investigated.
Results:
The total TORCH-IgM positive rate of the pregnant women was 4.11% (37/900). The IgM positive rates of CMV, HSV II , RV and TOX were 2.00% (18/900), 0.78% (7/900), 0.44% (4/900), and 0.89% (8/900) respectively. Thirty-one TORCH-IgM positive pregnant women continued their pregnancies and 20 of them were found abnormal pregnancy outcomes, accounting for 64.52%.
Conclusion:
TORCH infections are important risk factors responsible for abnormal pregnant outcomes. The screening of TORCH should be performed during pregnancy, and the appropriate interventions can reduce the occurrence of abnormal pregnancy and prevent birth defects.
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