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Published on: October 10, 2025
[Correlation between TORCH infections and abnormal pregnant outcomes].
Qian-Qian Zhang1, Jun-Zhen Cheng, Feng-Hui Wang
1Medical College of Yan'an University, Yan'an 716000, China.
Summary
TORCH infections significantly increase the risk of adverse pregnancy outcomes. Early screening and intervention for these infections during pregnancy are crucial for preventing birth defects.
Area of Science:
- Medical Microbiology
- Immunology
- Obstetrics
Context:
- TORCH infections are a group of congenital infections that can cause significant harm to the fetus.
- Understanding the prevalence and impact of TORCH infections is vital for maternal and child health.
- Adverse pregnancy outcomes associated with TORCH infections necessitate effective diagnostic and management strategies.
Purpose:
- To investigate the correlation between TORCH infections and adverse pregnancy outcomes.
- To determine the prevalence of TORCH-IgM antibodies in pregnant women.
- To provide evidence-based recommendations for birth defect interventions.
Summary:
- A study of 900 pregnant women found a 4.11% TORCH-IgM positive rate.
- Cytomegalovirus (CMV) was the most common infection (2.00%), followed by Toxoplasmosis (0.89%), Herpes Simplex Virus type II (HSV II) (0.78%), and Rubella (RV) (0.44%).
- Among TORCH-IgM positive women, 64.52% experienced abnormal pregnancy outcomes, highlighting a strong association.
Impact:
- TORCH infections are identified as significant risk factors for abnormal pregnancy outcomes.
- Routine screening for TORCH infections during pregnancy is recommended.
- Timely interventions can reduce the incidence of abnormal pregnancies and prevent congenital birth defects.
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