Related Experiment Videos
Orbital granuloma annulare as presentation of systemic sarcoidosis
Joann J Kang1, Vinay K Aakalu, Amy Lin
1Department of Ophthalmology and Visual Sciences and.
Purpose:
To report a unique case of an orbital mass with atypical histopathologic features that although overlap with other granulomatous disorders, likely represents orbital involvement of systemic sarcoidosis.
Methods:
Observational case report.
Results:
A 51-year-old woman presented with an orbital mass and was found to have mild proptosis and restriction of ocular motility. The remainder of her ophthalmic exam was unremarkable. Excisional biopsy revealed ill-defined granulomas with central necrosis, chronic inflammation and sclerotic collagen; several features consistent with granuloma annulare. Further systemic workup including laboratory and radiologic studies were compatible with a diagnosis of systemic sarcoidosis.
Conclusion:
Our case emphasizes the importance of a complete systemic workup with the detection of an orbital granuloma to ensure accurate diagnosis and appropriate management.
Related Concept Videos
Graves' Disease I: Introduction
Cirrhosis I: Introduction
Glaucoma: Overview
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Cushing Syndrome II: Pathophysiology
Graves Disease II: Pathophysiology