Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...
Type II Diabetes II: Pathophysiology01:24

Type II Diabetes II: Pathophysiology

PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
Type I Diabetes II: Pathophysiology01:26

Type I Diabetes II: Pathophysiology

Type 1 diabetes mellitus arises from an immune-mediated destruction of pancreatic β-cells, resulting in an absolute deficiency of insulin. This process develops in genetically susceptible individuals when autoimmunity, environmental exposures, and immunologic dysregulation converge to trigger a targeted attack on the insulin-producing cells of the pancreas. The β-cells are located within the islets of Langerhans and are essential for regulating blood glucose by facilitating cellular uptake of...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Align Then Tensorize: Multi-Level Consistent Anchor Graph Learning for Scalable Multi-View Clustering.

IEEE transactions on image processing : a publication of the IEEE Signal Processing Society·2026
Same author

19-Residue and 18-Residue Peptaibiotics Isolated from the Soil-Derived Fungus <i>Trichoderma</i> sp. XJ1083.

Journal of natural products·2026
Same author

Pyrazine Derivatives with Osteoclast Differentiation Inhibitory Activities from the Endophytic Fungus <i>Alternaria</i> sp. HJT-Y7.

Journal of natural products·2026
Same author

Undescribed polyketides and alkaloids from the endophytic fungus Penicillium steckii HJT-A-10.

Phytochemistry·2026
Same author

Dual-targeted hybrid micelles mediated by VCAM-1 suppress synovial angiogenesis in rheumatoid arthritis.

International immunopharmacology·2025
Same author

Preparation and application of citric acid crosslinked gelatin-polyvinyl alcohol composite films for active food packaging.

International journal of biological macromolecules·2025

Related Experiment Videos

[Type 2 diabetes with multiple splenic abscesses: a case report].

Wenbing Zou1, Fang Gao, Chuan Tang

  • 1Department of Endocrinology, Minzu Hospital of Guangxi Zhuang Autonomous Region, Nanning, China. zol0324@tom.com

Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University
|July 31, 2013
PubMed
Summary
This summary is machine-generated.

Diabetes increases infection risk, including rare splenic abscesses. This case highlights type 2 diabetes complications and the importance of prompt treatment for this serious condition.

Related Experiment Videos

Area of Science:

  • Internal Medicine
  • Infectious Diseases
  • Endocrinology

Background:

  • Diabetes mellitus is associated with increased susceptibility to infections due to factors like hyperglycemia, impaired immune function, and poor circulation.
  • Splenic abscess, a rare but serious complication, carries a high mortality rate, particularly in diabetic patients.
  • Type 2 diabetes specifically elevates the risk of developing splenic abscesses.

Observation:

  • The case involves a patient diagnosed with type 2 diabetes.
  • The patient presented with multiple splenic abscesses, a rare clinical manifestation.
  • This observation underscores the severe infectious complications that can arise in poorly controlled diabetes.

Findings:

  • Type 2 diabetes is a significant risk factor for splenic abscess development.
  • Prompt and effective medical and/or surgical intervention is crucial for reducing the high mortality associated with splenic abscesses in diabetic individuals.
  • The presence of multiple abscesses indicates a severe infectious process.

Implications:

  • Increased vigilance for splenic abscesses is warranted in diabetic patients presenting with fever or abdominal pain.
  • Early diagnosis and aggressive management are critical for improving outcomes in this high-risk population.
  • Further research into the specific mechanisms linking type 2 diabetes to splenic abscess formation may reveal novel therapeutic targets.