Candidate gene analysis: severe intraventricular hemorrhage in inborn preterm neonates
Ulrika Adén1, Aiping Lin, Waldemar Carlo
1Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
The Journal of Pediatrics
|July 31, 2013
Abstract:
Intraventricular hemorrhage (IVH) is a disorder of complex etiology. We analyzed genotypes for 7 genes from 224 inborn preterm neonates treated with antenatal steroids and grade 3-4 IVH and 389 matched controls. Only methylenetetrahydrofolate reductase was more prevalent in cases of IVH, emphasizing the need for more comprehensive genetic strategies.
