Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

AND-logic MRI contrast by water flux modulation.

Chemical science·2026

Same author

Slowing Down Water: Enhanced and Cation-responsive MRI Contrast.

Angewandte Chemie (International ed. in English)·2026

Same author

Widespread omission of aptamer-target binding verification in aptasensor development: Consequences for sensor performance and the need for a K<sub>d</sub> gate.

Biosensors & bioelectronics·2026

Same author

Halogen bonding and hydrogen bonding fluorescent anion sensing at the solid-liquid interface.

Chemical science·2026

Same author

Circulating tumour cells as a window into lethality in prostate cancer.

Nature reviews. Urology·2026

Same author

Organic functionality in responsive paramagnetic nanostructures.

Frontiers in chemistry·2025

Same journal

Propylene carbonate-PVDF-HFP/MXene-based self-powered biosensor for auxiliary detection of salivary exosomal miRNA-155 in pediatric asthma.

Biosensors & bioelectronics·2026

Same journal

Nanostructured zinc-coordination supraparticles on cellulose fibers: A 3D-Printed μ-FAD integrated smartphone platform for multiplexed salivary metabolic monitoring.

Biosensors & bioelectronics·2026

Same journal

Reliable biomarker monitoring at microneedle aptamer biosensors using a dual-frequency ratiometric approach: Overcoming signal drifts.

Biosensors & bioelectronics·2026

Same journal

Interfacial structure-modified nanozyme drives single-receptor-single-reaction-unit multichannel sensor array for pesticide discrimination.

Biosensors & bioelectronics·2026

Same journal

A real-time 5-hydroxytryptamine monitoring system applicable both in vitro and in vivo.

Biosensors & bioelectronics·2026

Same journal

Recent developments of textile-based triboelectric nanogenerators for smart sports applications.

Biosensors & bioelectronics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 9, 2026

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

Label free redox capacitive biosensing.

Flávio C Bedatty Fernandes¹, Márcio S Góes, Jason J Davis

¹Instituto de Química, Universidade Estadual Paulista, CP 355, 14800-900 Araraquara, São Paulo, Brazil.

Biosensors & Bioelectronics

|July 31, 2013

Summary

This summary is machine-generated.

This study introduces a new label-free biosensor that uses redox capacitance to detect biomarkers like C-reactive protein. This ultrasensitive method offers a highly specific and linear detection range for various analytes.

Keywords:

Biosensor Capacitance spectroscopy Immunosensors Redox capacitance

More Related Videos

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor

Published on: May 2, 2025

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Published on: September 10, 2014

Related Experiment Videos

Last Updated: May 9, 2026

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor

Published on: May 2, 2025

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Published on: September 10, 2014

Area of Science:

Electrochemistry
Biosensor technology
Biomarker detection

Background:

Surface-confined redox groups generate interfacial charging.
This charging is quantifiable via redox capacitance.
Impedance-derived capacitance spectroscopy can probe this signal.

Purpose of the Study:

To develop a novel transduction method for analyte detection.
To utilize interfacial charging for sensitive biosensing.
To demonstrate applicability using C-reactive protein (CRP) as a model biomarker.

Main Methods:

Fabrication of mixed molecular films with redox groups and recognition elements (antibodies).
Utilizing impedance-derived capacitance spectroscopy to probe interfacial charging.
Assessing the detection of specific analytes, exemplified by CRP.

Main Results:

The developed method sensitively transduces analyte recognition and binding.
Demonstrated label-free, ultrasensitive, and highly specific detection.
Achieved a good linear range for analyte quantification.

Conclusions:

Surface-confined redox groups provide a sensitive platform for biosensing.
This novel transduction method is versatile for various redox reporter-receptor combinations.
The assay is suitable for detecting biomarkers like CRP for medical diagnostics.