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Updated: May 9, 2026

Combined Infusion and Stimulation with Fast-Scan Cyclic Voltammetry (CIS-FSCV) to Assess Ventral Tegmental Area Receptor Regulation of Phasic Dopamine
06:40

Combined Infusion and Stimulation with Fast-Scan Cyclic Voltammetry (CIS-FSCV) to Assess Ventral Tegmental Area Receptor Regulation of Phasic Dopamine

Published on: April 23, 2020

Tipepidine activates VTA dopamine neuron via inhibiting dopamine D₂ receptor-mediated inward rectifying K⁺ current

R Hamasaki1, T Shirasaki, F Soeda

  • 1Department of Environmental and Molecular Health Sciences, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan.

Neuroscience
|July 31, 2013
PubMed

Keywords:
5-HTDAG protein-coupled inwardly rectifying potassium channelG-protein-coupled inwardly rectifying potassiumG-protein-coupled receptorGIRKGPCRI(Baclofen)I(DA(GIRK))I(DA)I(h)IPSCsNANATNAcOCDPBS.E.M.SERTSNcTBSTBSTTHTritonX-100 in TBSVTAacutely dissociated neuronbaclofen-induced currentdopaminedopamine D(2) receptor-mediated GIRK currentdopamine-induced currenthyperpolarization-activated cation currentinhibitory postsynaptic currentsnoradrenalinenoradrenaline transporternucleus accumbensobsessive–compulsive disorderpatch clampphosphate bufferserotoninserotonin transporterstandard error of the meansubstantia nigra pars compactatipepidinetris-buffered salinetyrosine hydroxylaseventral tegmental area

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