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Cervical squamous cell carcinoma metastatic to placenta

Nhu Thuy T Can1, Patricia Robertson, Charles J Zaloudek

  • 1Department of Pathology, University of Chicago, Chicago, IL 94143-0102, USA.

International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists
|July 31, 2013
PubMed

A pregnant 29-year-old gravida 4, para 3 woman with Stage IIB cervical cancer was admitted at 33 weeks and 4 days of gestation and delivered a healthy neonate. Her placenta was small but otherwise grossly unremarkable. Microscopic examination revealed metastatic squamous cell carcinoma. An immunohistochemical stain for p16 was positive in the carcinoma cells, supporting metastasis from the cervical tumor. Cervical squamous cell carcinoma metastatic to placenta is very rare. We report a case and discuss metastatic cancer during pregnancy with recommendations for infant follow-up.

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