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Updated: May 9, 2026
13:10
Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli
Published on: September 25, 2016
Nanotechnology for computed tomography: a real potential recently disclosed.
Nicolas Anton1, Thierry F Vandamme
1CNRS 7199, Laboratoire de Conception et Application de Molecules Bioactives, équipe de Pharmacie Biogalénique, Faculte de Pharmacie, University of Strasbourg, 74 route du Rhin, BP, 60024, F 67401 Illkirch Cedex, France, nanton@unistra.fr.
Pharmaceutical Research
|July 31, 2013
Summary
Nanomaterials offer advanced X-ray imaging contrast agents with longer blood circulation and targeted accumulation. This review explores nanotechnology
Area of Science:
- Nanomedicine
- Medical Imaging
- Materials Science
Background:
- Traditional contrast agents have limitations in half-life and targeting.
- Nanomaterials offer enhanced blood circulation and targeted accumulation in lesions.
- Heavy metal or iodinated-loaded nanoparticles show promise for X-ray absorption.
Purpose of the Study:
- To provide a state-of-the-art review of nanotechnology applications in X-ray imaging.
- To discuss and compare various nanotechnology-based solutions.
- To analyze the impact of nanomaterial properties on imaging efficiency and scalability.
Main Methods:
- Literature review of emerging nanotechnology applications in X-ray imaging.
- Comparative analysis of different nanomaterial compositions and formulations.
- Discussion of physicochemical properties influencing performance.
Main Results:
- Nanomaterials provide improved X-ray absorption compared to traditional agents.
- Targeting mechanisms (passive and active) enhance accumulation at lesion sites.
- Formulation and properties significantly affect imaging efficiency and industrial viability.
Conclusions:
- Nanotechnology presents a significant advancement in X-ray imaging contrast agents.
- Careful consideration of composition, formulation, and properties is crucial for clinical translation.
- Further research is needed to optimize nanomaterials for widespread industrial scaling.
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