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Related Experiment Video

Updated: May 9, 2026

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles
10:14

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles

Published on: March 6, 2016

An acoustofluidic micromixer based on oscillating sidewall sharp-edges.

Po-Hsun Huang1, Yuliang Xie, Daniel Ahmed

  • 1Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA. junhuang@psu.edu.

Lab on a Chip
|July 31, 2013
PubMed
Summary

Acoustic streaming using sharp edges in microfluidic channels enables rapid, homogeneous mixing. This simple, efficient micromixer design offers broad application potential.

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Area of Science:

  • Microfluidics
  • Acoustic streaming
  • Biomedical engineering

Background:

  • Microfluidic devices require efficient mixing for various applications.
  • Traditional mixing methods can be slow or complex.
  • Acoustic streaming offers a potential solution for rapid mixing.

Purpose of the Study:

  • To demonstrate rapid and homogeneous mixing in a microfluidic channel using acoustic streaming.
  • To investigate the effect of sharp-edge design on mixing performance.
  • To present a simple and efficient acoustic micromixer.

Main Methods:

  • Inducing acoustic streaming via oscillating sidewall sharp-edges in a microfluidic channel.
  • Optimizing the geometric design of the sharp-edges.
  • Evaluating mixing performance and speed.

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Microfluidic Mixers for Studying Protein Folding
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Microfluidic Mixers for Studying Protein Folding

Published on: April 10, 2012

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics
12:26

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

Related Experiment Videos

Last Updated: May 9, 2026

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles
10:14

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles

Published on: March 6, 2016

Microfluidic Mixers for Studying Protein Folding
12:42

Microfluidic Mixers for Studying Protein Folding

Published on: April 10, 2012

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics
12:26

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

Main Results:

  • Achieved rapid and homogeneous mixing within the microfluidic channel.
  • Demonstrated excellent mixing performance through optimized sharp-edge design.
  • Confirmed fast mixing speeds in the developed device.

Conclusions:

  • The sharp-edge-based acoustic micromixer provides an effective solution for rapid mixing.
  • The device's simplicity and efficiency make it suitable for diverse applications.
  • This technology holds promise for advancing microfluidic applications.