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Updated: May 9, 2026
High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes
Published on: July 25, 2015
Needle-core biopsy in the pathologic diagnosis of malignant lymphoma showing high reproducibility among pathologists
Qinglong Hu1, Hina Naushad, Qingmei Xie
1Department of Pathology, Alegent Creighton Health, Omaha, NE, USA. qinglonghu@hotmail.com
Objectives:
To evaluate the role of needle-core biopsy in the pathologic diagnosis of lymphoma.
Methods:
One hundred and five cases with clinical suspicion for lymphoma were studied by 3 hematopathologists mimicking daily diagnostic service. The diagnostic result sheets were analyzed for diagnostic accuracy and reproducibility. The histologic pattern recognition by the 3 hematopathologists was also analyzed.
Results:
The overall diagnostic accuracy, based on the consensus diagnosis, was 85% to 87%. High reproducibility of diagnosis in lymphoma was observed among pathologists. The tissue size was associated with the percentage of definitive diagnosis. Histologic patterns were well recognized on core tissues.
Conclusions:
Needle-core biopsy is an effective technique for the diagnosis of lymphoma and should be considered the first-line procedure for cases with suspicion for lymphoma.
