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Interventions for infantile esotropia

Sue Elliott1, Ayad Shafiq

  • 1OphthalmologyDepartment, Salisbury Health Care NHS Trust, Salisbury, UK. sue.elliott@salisbury.nhs.uk.

The Cochrane Database of Systematic Reviews
|July 31, 2013
PubMed

Insights

This review found no studies on infantile esotropia (IE) interventions. More high-quality trials are needed to determine the best treatments and optimal timing for managing this eye condition.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Strabismus Research

Background:

  • Infantile esotropia (IE) is characterized by inward deviation of the eyes.
  • Clinical management of IE lacks clarity regarding optimal intervention type and timing.
  • Evidence-based guidelines for IE treatment are insufficient.

Purpose of the Study:

  • To systematically review the effectiveness of surgical and non-surgical interventions for infantile esotropia.
  • To evaluate the impact of treatment age on outcomes in infantile esotropia.
  • To identify gaps in the literature for future research.

Main Methods:

  • Comprehensive search of multiple electronic databases (CENTRAL, MEDLINE, EMBASE, LILACS) and clinical trial registries.
  • Inclusion of randomized controlled trials comparing any intervention for infantile esotropia.
  • Manual searches of strabismology conference proceedings and direct contact with researchers.

Main Results:

  • No randomized controlled trials met the inclusion criteria for this review.
  • The available literature primarily consists of retrospective and prospective cohort studies.
  • No conclusions could be drawn regarding the effectiveness of specific interventions or optimal treatment age.

Conclusions:

  • The current evidence base for infantile esotropia management is inadequate.
  • High-quality randomized controlled trials are essential to resolve controversies in IE treatment.
  • Further research is needed to establish optimal surgical and non-surgical approaches and intervention timing for IE.
Abstract

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