Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

T Cell Types and Functions

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...

EPS and iPS Cells in Disease Research

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...

Pulmonary Tuberculosis II

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

Disorders of Leukocytes

Disorders of Leukocytes

Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...

Defense Against Bacterial Pathogens

Defense Against Bacterial Pathogens

The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Rational Prescribing Under Pressure: A World Health Organization Indicator and National Medical Commission Compliance Audit With Shift-Based Analysis of Emergency Prescriptions at a Tertiary Care Hospital in North India.

Cureus·2026

Same author

The COCOON trial: wrapping potent EGFR therapy in proactive supportive care.

Journal of thoracic disease·2026

Same author

Chronic kidney disease in cirrhosis: a study of inpatients from a global perspective.

Gut·2026

Same author

Exploring role of therapeutic plasma exchange for hepatitis A-related acute liver failure: An Indian multi-center cohort study.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology·2026

Same author

International Consensus on Severe Lung Cancer-The Second Edition.

Translational lung cancer research·2026

Same author

Successful Tarlatamab Rechallenge After Recurrent High-Grade Cytokine Release Syndrome in Chromothripsis-Mediated SCLC: A Case Report.

JTO clinical and research reports·2026

Same journal

An unusual formation of sciatic nerve.

Indian journal of medical sciences·2014

Same journal

Chronic myeloid leukemia with hyperdiploidy: a case report with review of literature.

Indian journal of medical sciences·2014

Same journal

A 24 year-old male with yellow nail syndrome having bronchiactasis without pleural effusion as a pulmonary manifestation.

Indian journal of medical sciences·2014

Same journal

Yellow oleander poisoning in eastern province: an analysis of admission and outcome.

Indian journal of medical sciences·2014

Same journal

Prevalence and determining factors of anemia and malnutrition among Egyptian children.

Indian journal of medical sciences·2014

Same journal

Autonomic system modification in Zen practitioners.

Indian journal of medical sciences·2014

See all related articles

Search research articles

Related Experiment Video

Updated: May 9, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Leprosy and psoriasis co-existence.

Rajat Thawani¹, Ashish Goel

¹Department of Medicine, University College of Medical Sciences and GTB Hospital, Delhi, India. rajat13@gmail.com

Indian Journal of Medical Sciences

|July 31, 2013

Summary

This summary is machine-generated.

Psoriasis and leprosy rarely occur together. A case study suggests psoriasis may protect against leprosy, a phenomenon needing further genetic and historical research for confirmation.

Related Experiment Videos

Last Updated: May 9, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

Dermatology
Immunology
Epidemiology

Background:

Psoriasis and leprosy are typically mutually exclusive conditions.
The prevalence of psoriasis in leprosy patients is exceptionally low (0.014%).

Observation:

A case report details a patient with psoriasis who subsequently developed leprosy after treatment.
This observation challenges the typical inverse relationship between the two diseases.

Findings:

A review of existing hypotheses suggests psoriasis may confer protection against the clinical progression of leprosy.
Historical data potentially indicates that increased psoriasis prevalence might correlate with decreased leprosy incidence.

Implications:

The findings suggest a potential inverse relationship between psoriasis and leprosy, where psoriasis might offer protection.
Further genetic and paleoepidemiological studies are required to validate this inverse phenomenon and its historical context.