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Updated: May 9, 2026

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
Published on: May 16, 2014
[Development of intelligent monolithic stationary phase for chromatography]
1CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Abstract:
In recent years, great attention has been paid to monolith, which is developed as a new generation of chromatographic stationary phase, due to its advantages of in-situ preparation, fast mass transfer and high permeability. Besides, as a class of functional materials, intelligent polymer could response to external environmental stimuli, such as temperature, pH, salt and so on. This intelligent polymer is usually modified onto solid support surface for fabrication of environmental responsive materials, which could be widely applied in drug release, chemical sensing, cell growth, etc. As a result, the construction of intelligent surface on monolith can provide new opportunities for its development in chromatography. This review summarizes the development of intelligent monolith as chromatographic stationary phase during recent years.
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