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Multiple Sclerosis l: Introduction

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Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...

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Updated: May 9, 2026

Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis

Modeling Multiple Sclerosis in the Two Sexes: MOG_35-55-Induced Experimental Autoimmune Encephalomyelitis

Published on: October 13, 2023

Multiple sclerosis in pregnancy.

Suzanne McMurtry Baird¹, Jennifer Dalton

¹Clinical Program Development, Texas Children's Hospital, Pavilion for Women, 6621 Fannin St, Houston, TX 77030, USA. vsbaird@texaschildrens.org

The Journal of Perinatal & Neonatal Nursing

|August 1, 2013

Summary

This summary is machine-generated.

Multiple sclerosis (MS) is a common neurologic disability affecting young women. This review discusses managing MS during pregnancy, covering preconceptual, antepartum, and postpartum care.

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Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis

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Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Area of Science:

Neurology
Reproductive Medicine
Women's Health

Background:

Multiple sclerosis (MS) is the most frequent chronic neurologic disability among young adults.
MS predominantly affects women of childbearing age (20-45 years).
Pregnancy in women with MS necessitates careful management due to disease and treatment considerations.

Purpose of the Study:

To provide a comprehensive overview of pregnancy-related issues in women with multiple sclerosis.
To guide healthcare providers on managing MS throughout the reproductive journey.
To emphasize the importance of preconceptual counseling for optimizing outcomes.

Main Methods:

Literature review focusing on multiple sclerosis and pregnancy.
Synthesis of current recommendations for managing MS during preconceptual, antepartum, and postpartum periods.
Discussion of medication safety and disease course in relation to pregnancy.

Main Results:

Pregnancy may have a variable effect on MS disease activity, with a general trend towards reduced relapse rates during pregnancy.
Careful planning and management can lead to successful pregnancy outcomes for women with MS.
Medication adjustments and monitoring are crucial for maternal and fetal well-being.

Conclusions:

Women with multiple sclerosis can achieve successful pregnancies with appropriate preconceptual counseling and ongoing management.
Multidisciplinary care is essential for addressing the complexities of MS during pregnancy, childbirth, and the postpartum period.
Further research is needed to fully understand the long-term effects of pregnancy on MS progression.