Related Experiment Video For Apical core biopsy
Updated: May 9, 2026

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients
Published on: February 28, 2018
Disseminated malignancy after extracorporeal life support and left ventricular assist device, diagnosed by left
Tine E Philipsen1, Tom Vermeulen, Viviane M Conraads
1Department of Cardiac Surgery, University Hospital Antwerp, Edegem, Belgium.
Abstract:
The left ventricular apical core biopsy performed during implantation of a left ventricular assist device (VAD) is a well-known diagnostic procedure in confirming cardiomyopathies leading to end-stage heart failure. We describe a patient in whom disseminated malignancy was revealed by means of the apical core biopsy after extracorporeal life support and left ventricular assist device implantation as a bridge to transplantation. This case emphasizes the importance of thorough oncological screening before VAD implantation and the possible consequences of circulating tumour cells in this device-assisted circulation.
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