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Orange/black discolouration of the bowel (at laparotomy) due to clofazimine
M N Merrett1, R W King, K E Farrell
1Department of Gastroenterology, Prince Henry's Hospital, Melbourne, Victoria, Australia.
The Australian and New Zealand Journal of Surgery
|August 1, 1990
Abstract:
Clofazimine, a commonly used anti-lepromatous drug, is now being prescribed for the treatment of pyoderma gangrenosum, a complication of inflammatory bowel disease. This drug can cause an obstructive exacerbation of Crohn's disease. Surgeons should be aware of the orange/black discolouration of the bowel, which may mimic ischaemia macroscopically. A case, the first reported in Australia, is described and the literature discussed.