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Published on: August 4, 2011
Trilateral retinoblastoma with unilateral eye involvement
Irfanullah Shah1, Adnan Baig, Abdul Razzaq
1Department of Neurosurgery, Chandka Medical College, Larkana. irfanullahshah@ymail.com
JPMA. the Journal of the Pakistan Medical Association
|August 2, 2013
Summary
Trilateral retinoblastoma (TRb), a rare cancer combining eye tumors with brain neoplasms, is presented in a unique case. This report details the first instance of TRb with a suprasellar mass documented in Pakistan.
Area of Science:
- Pediatric Oncology
- Neuro-oncology
- Ophthalmology
Background:
- Trilateral retinoblastoma (TRb) is a rare condition involving retinoblastoma and an intracranial neuroblastic tumor.
- It can be associated with both familial and sporadic forms of retinoblastoma.
- Primitive neuroectodermal tumors (PNETs) are often found in the pineal or sellar regions.
Observation:
- This report describes a 12-year-old boy diagnosed with unilateral retinoblastoma.
- The patient also presented with an ectopic suprasellar primitive neuroectodermal tumor (PNET).
Findings:
- This case represents a rare occurrence of trilateral retinoblastoma.
- The specific presentation involved a suprasellar PNET, a less common location for this combination.
Implications:
- This case expands the known spectrum of trilateral retinoblastoma presentations.
- It highlights the importance of considering intracranial involvement in retinoblastoma cases.
- This documentation is the first of its kind in Pakistan, contributing to regional medical literature.
