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Published on: October 2, 2020

Intradialytic hypotension is associated with dialytic age in patients on chronic hemodialysis

Maurizio Bossola1, Alice Laudisio, Manuela Antocicco

  • 1Hemodialysis Service, Department of Surgery, Catholic University of the Sacred Heart , Rome , Italy .

Renal Failure
|August 2, 2013
PubMed

Insights

Dialytic age (DA) is linked to a higher likelihood of intradialytic hypotension (IDH) and more frequent IDH events in chronic hemodialysis patients. Further research is needed to uncover the reasons behind this association.

Area of Science:

  • Nephrology
  • Cardiovascular Medicine

Background:

  • Intradialytic hypotension (IDH) is a frequent complication in patients undergoing chronic hemodialysis.
  • The specific determinants of IDH remain incompletely understood, necessitating further investigation.

Purpose of the Study:

  • To investigate the association between dialytic age (DA) and the occurrence of IDH in patients on chronic hemodialysis.
  • To determine if DA influences the frequency of IDH episodes.

Main Methods:

  • A cohort of 82 patients on chronic hemodialysis for over one year was studied between January 2012 and January 2013.
  • IDH was defined by a significant drop in systolic blood pressure or mean arterial pressure accompanied by clinical symptoms.
  • Linear and logistic regression analyses were employed to assess the adjusted relationship between DA and IDH events.

Main Results:

  • The average dialytic age (DA) was 92 ± 81 months.
  • Eleven patients (16%) experienced IDH.
  • DA was significantly associated with an increased probability of IDH (OR = 1.01; 95% CI = 1.01-1.02; p = 0.048) and a higher number of IDH events, even after adjusting for confounders.

Conclusions:

  • Dialytic age (DA) is a significant factor associated with an increased risk of intradialytic hypotension (IDH) and a greater number of IDH episodes.
  • Further studies are required to elucidate the underlying mechanisms driving the association between DA and IDH.
Abstract

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