Switchable mechanical DNA "arms" operating on nucleic acid scaffolds associated with electrodes or semiconductor...

Functional footholds linked to DNA scaffolds associated with surfaces provide nano-engineered assemblies acting as switching devices. By the assembly of a β-cyclodextrin receptor on one foothold, and a ferrocene-modified nucleic acid on a second foothold, the switchable and reversible, fuel-driven activation of "molecular arms" proceeds, transduced by electrochemical or optical signals.