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Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...

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Histopathological evaluation of facial melasma treated with oral tranexamic acid alone and in combination with ketotifen.

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GLP-1 Receptor Agonists and Acne: Evidence and Inference.

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Related Experiment Video

Updated: May 9, 2026

A Rat Model of Compound Acne
03:10

A Rat Model of Compound Acne

Published on: November 1, 2024

Evidence on acne therapy.

Caroline Sousa Costa1, Edileia Bagatin

  • 1Universidade Federal de São Paulo, Brazil. carolinescosta2@terra.com.br

Sao Paulo Medical Journal = Revista Paulista De Medicina
|August 2, 2013
PubMed
Summary
This summary is machine-generated.

Current acne vulgaris treatments often lack strong scientific evidence. This review highlights the latest topical and systemic options, emphasizing high-quality studies for effective acne management.

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Last Updated: May 9, 2026

A Rat Model of Compound Acne
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Area of Science:

  • Dermatology
  • Evidence-Based Medicine

Background:

  • Many common acne vulgaris treatments lack robust scientific evidence.
  • Clinical management of acne faces challenges due to insufficient research backing.

Purpose of the Study:

  • To provide an updated overview of topical and systemic acne vulgaris treatments.
  • To emphasize findings from systematic reviews and well-designed clinical trials.

Main Methods:

  • Systematic search of major medical databases.
  • Focus on information from high-level scientific evidence sources.

Main Results:

  • Identified gaps in evidence for optimal oral antibiotic dosing and duration.
  • Highlighted ongoing concerns regarding the safety of oral isotretinoin.

Conclusions:

  • There is a need for more research to support current acne treatment practices.
  • Further investigation is required into antibiotic resistance and isotretinoin safety.