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Updated: May 9, 2026

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Published on: October 22, 2014
Correlation between the brachial blood pressure values obtained using the cuff method and the central blood pressure
Hiroshi Kobayashi1, Mineko Kinou, Kenji Takazawa
1Department of Cardiology, Tokyo Medical University Hachioji Medical Center, Japan. koba-pci@tokyo-med.ac.jp
Insights
Central systolic blood pressure (cSBP) measured via catheter is higher than brachial systolic blood pressure (bSBP) from cuffs. This difference in elderly patients is due to cuff method underestimation of bSBP.
Area of Science:
- Cardiovascular physiology
- Medical device technology
- Clinical diagnostics
Background:
- Central systolic blood pressure (cSBP) is a key cardiovascular indicator.
- Discrepancies between cSBP (catheter) and brachial systolic blood pressure (bSBP) (cuff) measurements are common.
- Understanding these differences is crucial for accurate hypertension management.
Purpose of the Study:
- To investigate the reasons for higher cSBP values obtained via catheter compared to bSBP values obtained via cuff.
- To quantify the discrepancy between catheter-derived cSBP and cuff-derived bSBP.
- To determine if cuff-based bSBP underestimates direct catheter measurements.
Main Methods:
- Study included 20 patients undergoing coronary angiography (CAG).
- cSBP measured using a catheter-guided pressure wire inserted via the radial artery.
- bSBP measured using both the pressure guide wire and a standard cuff method.
Main Results:
- Catheter cSBP was 4.6 mmHg higher than cuff bSBP.
- Cuff bSBP was 8.3 mmHg lower than catheter-derived bSBP.
- Catheter cSBP was 1.7 mmHg lower than catheter-derived bSBP.
Conclusions:
- In elderly patients with coronary heart disease, higher cSBP from catheter measurements is observed.
- The cuff method significantly underestimates brachial systolic blood pressure (bSBP) by 8.3 mmHg compared to direct catheter measurement.
- This underestimation by the cuff method explains the higher cSBP readings when using a catheter.
Objective:
This study was designed to identify why the central blood pressure (cSBP) values obtained using the catheter method tend to be higher than brachial systolic blood pressure (bSBP) values obtained using the cuff method.
Methods:
This study enrolled 20 patients who underwent coronary angiography (CAG) (mean age, 68.9 years; 13 men). Using the catheter method, a pressure guide wire was inserted via the radial artery at the time of CAG to measure the cSBP. The guide wire was then removed and the bSBP was obtained using two methods (the pressure guide wire method and the cuff method). The cSBP obtained with the catheter and the bSBP obtained with the cuff were compared, as were the bSBP obtained with the cuff and the bSBP obtained with the catheter.
Results:
The cSBP obtained with the catheter was 4.6 mmHg higher than the bSBP obtained with the cuff. The bSBP obtained with the cuff was 8.3 mmHg lower than the bSBP obtained with the catheter. The cSBP obtained with the catheter was 1.7 mmHg lower than the bSBP obtained with the catheter.
Conclusion:
In elderly patients with evident or suspected coronary heart disease, the finding of a higher cSBP measured using the catheter method than the bSBP obtained using the cuff method is attributable to bSBP underestimation (by 8.3 mmHg) using the cuff method compared to the bSBP directly obtained using the catheter method.
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Sites for measuring blood pressure
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Assessment of blood pressure in brachial artery(one-step method)
Prepare for the Procedure:
Equipments Used To Measure Blood Pressure
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.

