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Updated: May 9, 2026

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice
Published on: September 13, 2024
Pigmented villonodular synovitis of the temporomandibular joint
Helen Giannakopoulos1, Joli C Chou, Peter D Quinn
1Department of Oral and Maxillofacial Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA. helen.giannakopoulos@uphs.upenn.edu
Abstract:
Pigmented villonodular synovitis (PVNS) is a proliferative disorder that affects synovium-lined joints, bursae, and tendon sheaths. It appears in both diffuse and localized forms, depending on the extent of synovial involvement. PVNS rarely involves the temporomandibular joint (TMJ); when it does, it manifests clinically as a slowly growing and painless preauricular mass that resembles a parotid tumor. TMJ dysfunction, paresthesia, and/or hearing loss can result. We present a case of a large extra-articular PVNS of the TMJ, and we review the literature.
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