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Related Concept Videos

Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Sutures of the Skull01:22

Sutures of the Skull

The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...

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Related Experiment Video

Updated: May 9, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
08:03

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model

Published on: November 4, 2025

Active aneurysmal bone cysts in children: possible evolution after biopsy.

Djamel Louahem1, Pascal Kouyoumdjian, Ismat Ghanem

  • 1Orthopaedic Pediatric Surgery Department, Service d'Orthopédie Infantile, Hôpital Lapeyronie, 34295 Montpellier Cedex 5, France.

Journal of Children'S Orthopaedics
|August 2, 2013
PubMed
Summary

Aneurysmal bone cysts (ABCs) in children may heal spontaneously after a biopsy alone, with healing observed in four out of five cases, particularly in pelvic locations. Close clinical and radiological monitoring is recommended for selected ABC cases post-biopsy.

Keywords:
AdolescentAneurysmal bone cystBenign bone tumourSpontaneous healing

Related Experiment Videos

Last Updated: May 9, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
08:03

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model

Published on: November 4, 2025

Area of Science:

  • Pediatric Orthopedics
  • Skeletal Pathology

Background:

  • Aneurysmal bone cysts (ABCs) in children often present aggressively, necessitating surgical intervention like curettage or excision.
  • These treatments carry risks of recurrence and complex reconstruction challenges.
  • Spontaneous maturation and ossification of ABCs can occur, but predicting this is difficult.

Purpose of the Study:

  • To report on five new cases of active aneurysmal bone cysts (ABCs) that demonstrated spontaneous healing after biopsy alone.
  • To evaluate the potential for non-operative management of ABCs following an incisional biopsy.

Main Methods:

  • Retrospective analysis of five pediatric patients diagnosed with active aneurysmal bone cysts (ABCs).
  • All patients underwent an incisional biopsy as the sole intervention for the cyst.
  • No further treatment was administered to the ABCs post-biopsy.

Main Results:

  • Four out of five ABC cases showed spontaneous healing, with three cases occurring in the pelvis.
  • Healing times varied, ranging from 12 to 36 months post-biopsy.
  • Two lesions initially increased in size after biopsy before secondary regression.

Conclusions:

  • Spontaneous healing of aneurysmal bone cysts (ABCs) after biopsy is a viable outcome in selected pediatric cases.
  • Clinical and radiological surveillance is crucial for monitoring ABCs post-biopsy.
  • While unpredictable, aggressive lesions require prompt treatment, while less aggressive or stable lesions may benefit from observation for potential spontaneous resolution.