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Forward Genetic Approaches in Chlamydia trachomatis
Published on: October 23, 2013
Chlamydia pneumoniae infection-associated erythema multiforme.
Shinsaku Imashuku1, Naoko Kudo
1Division of Pediatrics and Hematology, Takasago-seibu Hospital , Takasago, Japan.
Pediatric Reports
|August 2, 2013
Summary
Chlamydia pneumoniae (Cp) infection may trigger erythema multiforme (EM) in some patients. This study analyzed 7 cases, suggesting Cp should be considered alongside Herpes simplex virus (HSV) in EM diagnoses.
Area of Science:
- Infectious Diseases
- Dermatology
- Immunology
Background:
- Erythema multiforme (EM) is commonly associated with Herpes simplex virus (HSV) infections.
- Recent findings suggest Chlamydia pneumoniae (Cp) may also be an EM trigger, particularly in Japan.
Purpose of the Study:
- To investigate the role of Chlamydia pneumoniae (Cp) infection in erythema multiforme (EM) development.
- To analyze clinical cases of Cp-associated EM.
Main Methods:
- Retrospective analysis of EM cases diagnosed between 2011-2012.
- Diagnosis of Cp infection confirmed by elevated anti-Cp IgM titers (>2.00) using the HITAZYME-ELISA test.
Main Results:
- Seven cases of Cp-associated EM were identified (1 male, 6 females).
- The median age of affected individuals was 13 years (range: 3-29 years).
Conclusions:
- Chlamydia pneumoniae (Cp) infection is a potential cause of erythema multiforme (EM).
- Clinicians should consider Cp infection in EM differential diagnoses, alongside HSV and Mycoplasma pneumoniae.
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