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Polypoidal lesions in the nasal cavity

Kalpana Kumari M K1, Mahadeva K C

  • 1Associate Professor, Department of Pathology, M.S. Ramaiah Medical College , Karnataka, India .

Journal of Clinical and Diagnostic Research : JCDR
|August 2, 2013
PubMed
Abstract

Insights

Most nasal cavity polypoidal lesions are nonneoplastic. This study analyzed 100 cases, finding 66% nonneoplastic and 34% neoplastic, with benign and malignant tumors equally represented.

Area of Science:

  • Pathology
  • Otolaryngology
  • Oncology

Background:

  • Nasal polyps are growths from nasal and paranasal sinus mucosa, often linked to allergic rhinitis.
  • These lesions are typically movable and painless.

Purpose of the Study:

  • To investigate the histopathologic diversity of polypoidal lesions within the nasal cavity.
  • To classify these lesions as neoplastic or nonneoplastic.

Main Methods:

  • Histopathologic examination of 100 consecutive nasal cavity polypoidal lesions.
  • Routine Hematoxylin and Eosin staining, with Periodic Acid Schiff (PAS) stains applied as needed.
  • Classification based on WHO criteria for neoplastic lesions.

Main Results:

  • Out of 100 cases, 66% were nonneoplastic and 34% were neoplastic.
  • Benign and malignant neoplastic lesions were equally represented (17 cases each).
  • Inflammatory and allergic nasal polyps constituted 44% of cases; anaplastic carcinoma was the most common malignancy.

Conclusions:

  • The predominant diagnosis for polypoidal lesions in the nasal cavity is nonneoplastic.
  • Age and sex influenced the prevalence of neoplastic versus nonneoplastic lesions.
Keywords:
AllergicAngiofibromaInflammatoryNasal cavityNonneoplasticPolyps

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