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Rhino-orbital mucormycosis in diabetes mellitus

Ravindra V Shinde1, Geeta S Karande, S T Mohite

  • 1Assistant Professor, Department of Microbiology, Krishna Institute of Medical Sciences , Karad-415110, India .

Journal of Clinical and Diagnostic Research : JCDR
|August 2, 2013
PubMed

Insights

Rhino-orbital mucormycosis is a rare, life-threatening fungal infection often seen in immunocompromised individuals, particularly those with diabetes. Prompt diagnosis and treatment are crucial for survival due to its rapid progression and high mortality rate.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Ophthalmology

Background:

  • Rhino-orbital mucormycosis is a rare, aggressive fungal infection.
  • It primarily affects patients with diabetes mellitus and other immune deficiencies.
  • The condition is a medical emergency with a high mortality rate.

Purpose of the Study:

  • To highlight the critical nature of rhino-orbital mucormycosis.
  • To emphasize the importance of early recognition and treatment.
  • To discuss the increasing frequency of fungal infections in immunocompromised patients.

Main Methods:

  • Review of clinical cases and literature.
  • Analysis of diagnostic challenges.
  • Evaluation of treatment outcomes.

Main Results:

  • Rhino-orbital mucormycosis progresses rapidly, often leading to death within days.
  • Early intervention significantly improves patient outcomes.
  • Immune deficiency is a major predisposing factor.

Conclusions:

  • Rhino-orbital mucormycosis requires immediate medical attention.
  • Aggressive management is essential for patient survival.
  • Increased vigilance is needed for fungal infections in at-risk populations.
Keywords:
Diabetes mellitusMucormycosisRhizopus spp

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