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Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...

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Related Experiment Video

Updated: May 9, 2026

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy
07:43

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy

Published on: July 2, 2021

Diagnosing and managing hip problems in childhood.

James S Huntley1

  • 1Royal Hospital for Sick Children, Yorkhill, Glasgow, UK.

The Practitioner
|August 3, 2013
PubMed
Summary

Pediatric hip conditions, including developmental dysplasia of the hip (DDH), require careful diagnosis. Early identification of limping causes like infection is crucial for timely treatment and preventing long-term morbidity.

Area of Science:

  • Pediatric Orthopedics
  • Pediatric Rheumatology
  • Pediatric Infectious Diseases

Background:

  • Hip and surrounding tissues are involved in numerous childhood conditions.
  • Developmental dysplasia of the hip (DDH) is a common cause of morbidity, with idiopathic being the most frequent type.
  • Neonatal hip screening uses Ortolani and Barlow maneuvers, but late diagnoses occur due to test limitations.

Purpose of the Study:

  • To review the differential diagnosis of hip conditions in children.
  • To emphasize the importance of considering less common diagnoses in limping children.
  • To highlight the critical need for early diagnosis and treatment of pediatric hip infections.

Main Methods:

  • Review of common and less common pediatric hip pathologies.

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  • Discussion of diagnostic challenges in developmental dysplasia of the hip.
  • Emphasis on clinical presentation of infection in limping children.

    • Main Results:

    • The hip joint is the most frequent site of pathology in limping children.
    • Transient synovitis accounts for 40% of diagnosed hip conditions.
    • Infections like septic arthritis require urgent diagnosis and treatment.

    Conclusions:

    • Accurate history and examination are key to diagnosing pediatric hip conditions.
    • Fever, focal tenderness, and restricted movement in a limping child suggest infection.
    • Prompt investigation and management are vital for favorable outcomes in pediatric hip disease.